OSCC-074-04-1A
De-identified Human Immune Atlas donor/sample detail for CancerSCEM 2.0. The record preserves available public metadata while avoiding direct identifiers.
Donor-Level Analysis Results
Matrix-backed CancerSCEM donor analysis for OSCC-074-04-1A, generated 2026-07-09 12:54:49 +0800.
2,000Cells analyzed
10Clusters
7,872Expressed genes
637.9Mean genes
Gene Program Summary
| Program | Clusters | Mean Score | Max Score | Genes Used |
|---|---|---|---|---|
| Myeloid_APC | 10 | 0.6087 | 2.2119 | 5 |
| B_plasma | 10 | 0.5217 | 1.2249 | 4 |
| Epithelial_tumor | 10 | 0.4473 | 1.1151 | 3 |
| T_NK_cytotoxic | 10 | 0.1581 | 0.5949 | 3 |
| Proliferation | 10 | 0.1072 | 0.3195 | 2 |
| Checkpoint_exhaustion | 10 | 0.0328 | 0.1144 | 4 |
| Fibroblast_stroma | 10 | 0.0066 | 0.018 | 2 |
| Endothelial | 10 | 0.0004 | 0.0036 | 1 |
Cluster QC
| Cluster | Cells | Mean UMI | Median Genes | Mean Mito % |
|---|---|---|---|---|
| cluster_8 | 351 | 1317 | ||
| cluster_6 | 308 | 144 | ||
| cluster_2 | 293 | 575 | ||
| cluster_7 | 223 | 1210 | ||
| cluster_4 | 216 | 302 | ||
| cluster_9 | 203 | 205 | ||
| cluster_3 | 164 | 521.5 | ||
| cluster_5 | 119 | 493 | ||
| cluster_10 | 68 | 256.5 | ||
| cluster_1 | 55 | 526 |
Top Cluster Marker Genes
| Cluster | Rank | Gene | Score | Mean Expr | Detect Fraction |
|---|---|---|---|---|---|
| cluster_10 | 1 | SPRR3 | 4.6484 | 5.2795 | 1 |
| cluster_7 | 1 | S100A2 | 3.3552 | 4.6138 | 1 |
| cluster_9 | 1 | FDCSP | 3.3217 | 3.4649 | 1 |
| cluster_8 | 1 | MIR205HG | 2.6262 | 3.0277 | 1 |
| cluster_2 | 1 | PTPRC | 1.8098 | 2.0717 | 0.9829 |
| cluster_3 | 1 | MUC7 | 1.6853 | 3.9248 | 0.9878 |
| cluster_6 | 1 | IGKC | 1.3534 | 2.1933 | 0.8084 |
| cluster_1 | 1 | PTPRC | 1.2914 | 1.7829 | 0.9273 |
| cluster_4 | 1 | MUC7 | 0.8822 | 3.1646 | 0.9491 |
| cluster_5 | 1 | PTPRC | 0.4369 | 0.9379 | 0.5294 |
| cluster_10 | 2 | S100A9 | 4.5551 | 5.7153 | 1 |
| cluster_7 | 2 | S100A11 | 3.0926 | 4.4678 | 1 |
| cluster_8 | 2 | ATF3 | 2.5792 | 3.3303 | 1 |
| cluster_9 | 2 | MUC7 | 2.493 | 4.6176 | 0.9901 |
| cluster_2 | 2 | STAT4 | 1.4861 | 1.6346 | 0.9317 |
| cluster_3 | 2 | JCHAIN | 1.2482 | 1.731 | 0.5061 |
| cluster_6 | 2 | JCHAIN | 1.124 | 1.5361 | 0.5682 |
| cluster_1 | 2 | ARHGAP15 | 0.8562 | 1.1257 | 0.8182 |
| cluster_4 | 2 | STATH | 0.8271 | 2.3819 | 0.8519 |
| cluster_5 | 2 | ZBTB20 | 0.3549 | 0.8584 | 0.6387 |
| cluster_10 | 3 | S100A8 | 4.3798 | 5.2867 | 1 |
| cluster_7 | 3 | CSTA | 3.0226 | 3.6747 | 0.991 |
| cluster_9 | 3 | STATH | 2.4218 | 3.82 | 0.9803 |
| cluster_8 | 3 | S100A2 | 2.3798 | 3.5949 | 1 |
| cluster_2 | 3 | CXCR4 | 1.4803 | 1.6091 | 0.901 |
| cluster_3 | 3 | PIGR | 1.0273 | 1.6116 | 0.6098 |
| cluster_1 | 3 | CD52 | 0.843 | 1.0944 | 0.7455 |
| cluster_4 | 3 | PIGR | 0.6005 | 1.2042 | 0.5324 |
| cluster_6 | 3 | MZB1 | 0.3548 | 0.4668 | 0.2825 |
| cluster_5 | 3 | ARHGAP26 | 0.311 | 0.5555 | 0.4622 |
| cluster_10 | 4 | CSTA | 3.0243 | 3.9107 | 1 |
| cluster_7 | 4 | S100A9 | 2.9488 | 3.9352 | 0.9865 |
| cluster_8 | 4 | IL1R2 | 2.1383 | 2.2522 | 0.9858 |
| cluster_9 | 4 | PIGR | 1.4162 | 1.9411 | 0.9113 |
| cluster_2 | 4 | RUNX3 | 1.3382 | 1.4698 | 0.9044 |
| cluster_3 | 4 | S100A1 | 0.9623 | 1.3084 | 0.561 |
| cluster_1 | 4 | MBNL1 | 0.8353 | 1.6196 | 0.9273 |
| cluster_4 | 4 | ODAM | 0.4664 | 0.8483 | 0.4306 |
| cluster_5 | 4 | STAT4 | 0.3065 | 0.6545 | 0.4034 |
| cluster_6 | 4 | TXNDC5 | 0.1593 | 0.3454 | 0.2695 |
Primary Metadata
Core de-identified metadata fields migrated from the ImmuneAging donor manifest.
Donor ID
OSCC-074-04-1A
Sample ID
OSCC-074-04-1A
Dataset
CancerSCEM 2.0
Cohort
CancerSCEM 2.0 Chinese subset; Oral Squamous Cell Carcinoma
Age / Age Group
Pan-cancer Chinese cohort, per-donor ages not in CancerSCEM metadata
Sex
Not reported in public CancerSCEM metadata
Health Status
Oral Squamous Cell Carcinoma; Normal
Tissue / Cell Source
Normal
Modality
scRNA-seq (10X Genomics)
Cell Count
8,667
Analysis Status
Matrix available; UMAP generated by fallback sampled pipeline
UMAP Status
Ready
Metadata / Source Notes
Project ID: OSCC-074; Cancer type: Oral Squamous Cell Carcinoma; Source: NCBI (GEO); Accession: GSE193766; Country: CHN; Sample type: Normal; Protocol: 10X Genomics; Matrix: OSCC-074-04-1A.counts.matrix.tsv.gz (6.98 MB); Matrix integrity: gzip file ended before end-of-stream marker during UMAP generation; redownload required before UMAP can be generated.; Age/sex not reported in public CancerSCEM metadata. Age source: CancerSCEM 2.0 database; 400 samples across 47 cancer types; donor-level age not included in download.csv
Additional Clinical / Source Fields
Supplementary source metadata retained from the migrated manifest where available.
cancer type
Oral Squamous Cell Carcinoma
cancer type short
OSCC
library count
1
library sample ids
OSCC-074-04-1A
source reference
CancerSCEM 2.0 metadata table; data source=NCBI (GEO); accession=GSE193766; downloaded 2026-07-06
data accession
GSE193766
project id
OSCC-074
sample type
Normal
country
CHN
data source
NCBI (GEO)
accession no
GSE193766
construction protocol
10X Genomics
transcriptome profile
Yes
metabolic profile
Yes
matrix status
Matrix incomplete; redownload required
matrix file name
OSCC-074-04-1A.counts.matrix.tsv.gz
matrix file size bytes
7323393
matrix file size mb
6.98
umap coordinates url
umap summary url
umap pipeline
Fallback Python normalize_total/log1p/HVG/SVD/UMAP; sampled 3000/8667 cells; generated 2026-07-09
matrix integrity status
Gzip EOF/truncated during UMAP generation