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PDAC-046-12-1A

De-identified Human Immune Atlas donor/sample detail for CancerSCEM 2.0. The record preserves available public metadata while avoiding direct identifiers.

Donor-Level Analysis Results

Matrix-backed CancerSCEM donor analysis for PDAC-046-12-1A, generated 2026-07-09 12:54:49 +0800.

2,000Cells analyzed
18Clusters
23,275Expressed genes
7008Mean UMI
2213Mean genes
5.208Mean mito %
Donor-level analysis panel
Cluster cell counts, cluster-by-program score heatmap, and top marker genes.
Gene Program Summary
Program Clusters Mean Score Max Score Genes Used
B_plasma 18 0.5656 2.2991 8
T_NK_cytotoxic 18 0.2692 1.2573 10
Myeloid_APC 18 0.2446 0.9139 9
Checkpoint_exhaustion 18 0.1738 0.6627 8
Endothelial 18 0.064 0.6023 7
Proliferation 18 0.0469 0.2777 7
Fibroblast_stroma 18 0.0352 0.4848 8
Epithelial_tumor 18 0.0028 0.0158 7
Cluster QC
Cluster Cells Mean UMI Median Genes Mean Mito %
cluster_1 358 8171.9804 2475.5 6.061
cluster_2 321 8054.7009 2470 6.8277
cluster_3 312 6582.4071 1968.5 4.4044
cluster_4 242 6483.0207 2096 4.3949
cluster_5 168 5219.5774 1923 5.4882
cluster_6 146 6363.9384 2042.5 4.5846
cluster_7 110 5130.9364 1882 5.3699
cluster_8 53 2457.2264 923 1.3024
cluster_9 46 7589.6957 2352.5 4.8386
cluster_10 43 7128.4419 2499 6.3757
cluster_11 43 7487.093 1596 3.9857
cluster_12 35 5682.7143 1953 3.8522
cluster_13 33 8520.3939 1822 4.2242
cluster_14 24 7019.25 2048 5.8578
cluster_15 24 7601.8333 2441 5.0115
cluster_16 21 17767.0476 2298 1.6226
cluster_17 14 7975.9286 2618 5.9186
cluster_18 7 12624.4286 2907 6.4429
Top Cluster Marker Genes
Cluster Rank Gene Score Mean Expr Detect Fraction
cluster_16 1 IGKC 5.0142 5.8789 0.8571
cluster_18 1 BIRC3 3.5824 4.2043 1
cluster_8 1 S100A9 3.0954 3.1081 1
cluster_15 1 NKG7 2.5126 2.6351 1
cluster_17 1 CD83 2.2082 3.1485 1
cluster_2 1 HLA-DRA 2.0734 3.0541 1
cluster_5 1 CCL4 2.0586 2.259 0.8095
cluster_1 1 BANK1 2.0088 2.6729 0.9972
cluster_12 1 MT2A 1.8794 2.2028 0.8571
cluster_9 1 TOX 1.8175 2.2758 0.9783
cluster_10 1 AFF3 1.7271 2.825 1
cluster_7 1 CCL5 1.648 1.8904 0.9273
cluster_13 1 CST3 1.6467 1.6787 0.7576
cluster_14 1 LINC02446 1.6402 1.6723 0.9583
cluster_4 1 IL7R 1.4236 2.3904 0.9587
cluster_3 1 PDE3B 1.3951 2.1797 0.9744
cluster_6 1 AL136456.1 1.3082 1.4013 0.6027
cluster_11 1 ACTG1 1.3048 2.5147 0.9767
cluster_16 2 IGHG4 3.9745 4.0764 0.8095
cluster_18 2 UVRAG 3.0578 3.6145 1
cluster_8 2 NAMPT 2.6816 3.0876 1
cluster_15 2 CCL4 2.4173 2.7615 0.9167
cluster_2 2 CD74 1.8969 3.0392 1
cluster_1 2 AFF3 1.8453 2.6501 0.9944
cluster_9 2 SRGN 1.8143 3.4571 1
cluster_12 2 SPARCL1 1.7986 1.8079 0.6571
cluster_5 2 CCL5 1.7829 1.9661 0.9405
cluster_17 2 EGR3 1.7527 1.8259 1
cluster_13 2 LYZ 1.6449 1.6588 0.6364
cluster_14 2 PDE3B 1.5619 2.5454 1
cluster_10 2 HLA-DRA 1.5145 2.7954 1
cluster_3 2 IL7R 1.3656 2.2916 0.9936
cluster_11 2 HLA-DRA 1.2795 2.5654 0.907
cluster_7 2 IL7R 1.2748 2.3437 0.9455
cluster_6 2 SKAP1 1.1724 1.7882 0.9589
cluster_4 2 SRGN 1.0946 2.6466 0.9917
cluster_16 3 IGHG1 3.4219 3.5356 0.6667
cluster_18 3 ID2 2.955 3.1962 1
cluster_8 3 IL1R2 2.6399 2.6848 1
cluster_15 3 KLRD1 2.2215 2.2659 1

Primary Metadata

Core de-identified metadata fields migrated from the ImmuneAging donor manifest.

Donor ID
PDAC-046-12-1A
Sample ID
PDAC-046-12-1A
Dataset
CancerSCEM 2.0
Cohort
CancerSCEM 2.0 Chinese subset; Pancreatic Ductal Adenocarcinoma
Age / Age Group
Pan-cancer Chinese cohort, per-donor ages not in CancerSCEM metadata
Sex
Not reported in public CancerSCEM metadata
Health Status
Pancreatic Ductal Adenocarcinoma; Normal
Tissue / Cell Source
Normal
Modality
scRNA-seq (10X Genomics)
Cell Count
5,736
Analysis Status
Matrix available; UMAP generated
UMAP Status
Ready
Metadata / Source Notes
Project ID: PDAC-046; Cancer type: Pancreatic Ductal Adenocarcinoma; Source: NCBI (GEO); Accession: GSE212966; Country: CHN; Sample type: Normal; Protocol: 10X Genomics; Matrix: PDAC-046-12-1A.counts.matrix.tsv.gz (13.95 MB); UMAP: Scanpy-generated donor-level UMAP preview; cells=5736; raw genes=24427; Leiden clusters=18; coordinates TSV and summary JSON are available online.; Age/sex not reported in public CancerSCEM metadata. Age source: CancerSCEM 2.0 database; 400 samples across 47 cancer types; donor-level age not included in download.csv

Additional Clinical / Source Fields

Supplementary source metadata retained from the migrated manifest where available.

cancer type
Pancreatic Ductal Adenocarcinoma
cancer type short
PDAC
library count
1
library sample ids
PDAC-046-12-1A
source reference
CancerSCEM 2.0 metadata table; data source=NCBI (GEO); accession=GSE212966; downloaded 2026-07-06
data accession
GSE212966
project id
PDAC-046
sample type
Normal
country
CHN
data source
NCBI (GEO)
accession no
GSE212966
construction protocol
10X Genomics
transcriptome profile
Yes
metabolic profile
Yes
matrix status
Matrix available
matrix file name
PDAC-046-12-1A.counts.matrix.tsv.gz
matrix file size bytes
14626545
matrix file size mb
13.95
matrix download url
umap coordinates url
umap summary url
umap pipeline
Scanpy 1.9.8 normalize_total/log1p/HVG/PCA/neighbors/leiden/umap; cells=5736; raw_genes=24427; leiden_clusters=18; generated 2026-07-07
matrix integrity status
Gzip readable; UMAP generated