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PTC-069-02-1A

De-identified Human Immune Atlas donor/sample detail for CancerSCEM 2.0. The record preserves available public metadata while avoiding direct identifiers.

Donor-Level Analysis Results

Matrix-backed CancerSCEM donor analysis for PTC-069-02-1A, generated 2026-07-09 12:54:49 +0800.

2,000Cells analyzed
16Clusters
24,587Expressed genes
9150Mean UMI
2786Mean genes
4.366Mean mito %
Donor-level analysis panel
Cluster cell counts, cluster-by-program score heatmap, and top marker genes.
Gene Program Summary
Program Clusters Mean Score Max Score Genes Used
B_plasma 16 0.7682 2.3284 8
T_NK_cytotoxic 16 0.4309 1.435 10
Checkpoint_exhaustion 16 0.2642 0.8707 8
Myeloid_APC 16 0.2331 1.5209 9
Endothelial 16 0.1329 1.3425 7
Fibroblast_stroma 16 0.1131 1.3145 8
Proliferation 16 0.0833 0.4229 7
Epithelial_tumor 16 0.0342 0.3641 7
Cluster QC
Cluster Cells Mean UMI Median Genes Mean Mito %
cluster_1 300 9804.42 2828.5 4.625
cluster_2 219 7369.9361 2580 5.1532
cluster_3 178 9436.0787 3184 4.763
cluster_4 178 10230.5169 2947.5 5.3611
cluster_5 171 8318.0994 2899 5.2455
cluster_6 136 10706.0809 3698.5 3.0643
cluster_7 130 6717.8692 2844 4.2342
cluster_8 119 7527.6555 2988 5.2051
cluster_9 98 15906.6224 970 2.1208
cluster_10 93 8165.6344 2886 1.8856
cluster_11 87 8988.0345 2549 4.8162
cluster_12 81 9331.0494 3139 4.2507
cluster_13 69 8776.0145 2948 5.268
cluster_14 66 6281.0606 2410 2.2768
cluster_15 48 12694.0625 3916.5 4.1931
cluster_16 27 4119.2593 758 2.5505
Top Cluster Marker Genes
Cluster Rank Gene Score Mean Expr Detect Fraction
cluster_9 1 IGHG4 4.577 5.2656 1
cluster_8 1 IGFBP7 3.4719 3.8109 0.958
cluster_10 1 BANK1 2.8112 3.1002 0.9892
cluster_4 1 HLA-DRA 2.7582 3.6278 1
cluster_7 1 IGFBP7 2.3567 2.7491 0.9154
cluster_5 1 NKG7 2.2699 2.5906 0.9474
cluster_6 1 LRMP 2.2151 2.5295 0.9118
cluster_15 1 LYZ 2.1798 2.231 0.8333
cluster_2 1 CCL5 2.0414 2.5258 0.9772
cluster_13 1 CCL5 2.0369 2.6746 0.942
cluster_12 1 IL32 2.0079 3.1266 0.963
cluster_1 1 PDE3B 1.901 2.4715 0.9367
cluster_16 1 CLU 1.8968 2.0477 1
cluster_3 1 TOX 1.8964 2.6073 0.9775
cluster_11 1 JUNB 1.7094 3.7994 1
cluster_14 1 LEF1 1.2025 1.4723 0.7727
cluster_9 2 IGKC 4.5007 6.1625 0.9898
cluster_8 2 MGP 2.7496 3.0209 0.9244
cluster_4 2 CD83 2.6243 3.1745 0.9831
cluster_10 2 AFF3 2.3787 2.8257 1
cluster_7 2 A2M 2.2673 2.5032 0.9
cluster_5 2 GNLY 2.1617 2.1919 0.7018
cluster_15 2 TYROBP 2.0993 2.1775 0.8333
cluster_6 2 HLA-DRA 2.0651 3.0397 0.9412
cluster_2 2 GZMK 1.9097 2.0469 0.8904
cluster_1 2 IL7R 1.8522 2.5949 0.97
cluster_3 2 RNF19A 1.8314 2.6035 0.9888
cluster_13 2 CCL4 1.7115 2.2689 0.942
cluster_11 2 JUN 1.6595 3.5755 1
cluster_12 2 IKZF2 1.6527 1.8092 0.8889
cluster_16 2 TG 1.6417 1.862 0.8148
cluster_14 2 LINC00861 1.1201 1.3825 0.803
cluster_9 3 IGHG3 4.3739 5.1558 0.9592
cluster_8 3 PRKG1 2.3853 2.432 0.8824
cluster_4 3 CD74 2.2737 3.7627 1
cluster_10 3 CD74 2.2067 3.7955 1
cluster_7 3 PTPRG 2.116 2.3146 0.9077
cluster_5 3 CCL5 2.1129 2.6402 0.924
cluster_15 3 FTL 2.0299 3.961 1
cluster_6 3 CD74 1.9644 3.5221 0.9853

Primary Metadata

Core de-identified metadata fields migrated from the ImmuneAging donor manifest.

Donor ID
PTC-069-02-1A
Sample ID
PTC-069-02-1A
Dataset
CancerSCEM 2.0
Cohort
CancerSCEM 2.0 Chinese subset; Papillary Thyroid Carcinoma
Age / Age Group
Pan-cancer Chinese cohort, per-donor ages not in CancerSCEM metadata
Sex
Not reported in public CancerSCEM metadata
Health Status
Papillary Thyroid Carcinoma; Tumour
Tissue / Cell Source
Tumour
Modality
scRNA-seq (10X Genomics)
Cell Count
2,530
Analysis Status
Matrix available; UMAP generated
UMAP Status
Ready
Metadata / Source Notes
Project ID: PTC-069; Cancer type: Papillary Thyroid Carcinoma; Source: NCBI (GEO); Accession: GSE191288; Country: CHN; Sample type: Tumour; Protocol: 10X Genomics; Matrix: PTC-069-02-1A.counts.matrix.tsv.gz (7.93 MB); UMAP: Scanpy-generated donor-level UMAP preview; cells=2530; raw genes=25385; Leiden clusters=16; coordinates TSV and summary JSON are available online.; Age/sex not reported in public CancerSCEM metadata. Age source: CancerSCEM 2.0 database; 400 samples across 47 cancer types; donor-level age not included in download.csv

Additional Clinical / Source Fields

Supplementary source metadata retained from the migrated manifest where available.

cancer type
Papillary Thyroid Carcinoma
cancer type short
PTC
library count
1
library sample ids
PTC-069-02-1A
source reference
CancerSCEM 2.0 metadata table; data source=NCBI (GEO); accession=GSE191288; downloaded 2026-07-06
data accession
GSE191288
project id
PTC-069
sample type
Tumour
country
CHN
data source
NCBI (GEO)
accession no
GSE191288
construction protocol
10X Genomics
transcriptome profile
Yes
metabolic profile
Yes
matrix status
Matrix available
matrix file name
PTC-069-02-1A.counts.matrix.tsv.gz
matrix file size bytes
8313363
matrix file size mb
7.93
matrix download url
umap coordinates url
umap summary url
umap pipeline
Scanpy 1.9.8 normalize_total/log1p/HVG/PCA/neighbors/leiden/umap; cells=2530; raw_genes=25385; leiden_clusters=16; generated 2026-07-07
matrix integrity status
Gzip readable; UMAP generated