⚙ How is this computed? Methods: Correlation Analysis
Longevity · Real single-cell summary

Longevity signature by Cell Type

Respiratory system illustration
sys04 · Respiratory system
System introduction

Respiratory system

The respiratory system facilitates gas exchange between the body and the environment. Its primary organs are the lungs and the airways (nose, pharynx, larynx, trachea, bronchi). The system's core function is to supply oxygen to the bloodstream and remove carbon dioxide. This occurs in the alveoli, tiny air sacs where diffusion takes place. It also plays roles in vocalization, olfaction, and regulating blood pH.

Source: LACA body-system catalog

Observed descriptive scores for the predefined 15-gene longevity signature in SP121's selected system. Values are read from the published system payload.

SP121 · Respiratory system70,218 cells15 cell types
Download summary CSV →Open source analysis →
0.08109Overall mean score
0.08053Overall median
0.1514895th percentile
95.25%Cells with score > 0
FibroblastsHighest observed mean score
Selected system

Cell-type summary

Filter by system or cell type. “Positive” means score greater than zero; it is not a p-value or enrichment call.

RankCell typeCellsMean scorePositive cellsMaximumSampling note
Method & provenance

Dataset contract

Equal-weight species-calibrated score

mean(clip(matrix_value / species_positive_q99, 0, 1))

  • Each mapped gene is scaled by its 99th percentile among positive cells in the complete source-species H5AD.
  • The same 15 mapped genes and SP121 species calibration are used for every system.
  • The score is descriptive relative expression on a 0–1 scale.

Pinned analyzed release

Release: r20260808-v4
Source file: SP121.h5ad
Cell-type key: laca_curated_celltype_v3
Generated: 2026-08-07T17:18:37.717277+00:00

Raw JSON →