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ESCC-111-07-1A

De-identified Human Immune Atlas donor/sample detail for CancerSCEM 2.0. The record preserves available public metadata while avoiding direct identifiers.

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Donor-Level Analysis Results

Matrix-backed CancerSCEM donor analysis for ESCC-111-07-1A, generated 2026-07-09 12:54:49 +0800.

1,998Cells analyzed
22Clusters
22,940Expressed genes
7679Mean UMI
1979Mean genes
2.999Mean mito %
Donor-level analysis panel
Cluster cell counts, cluster-by-program score heatmap, and top marker genes.
CancerSCEM Deep Analysis Donor JSON UMAP Coordinates UMAP Summary
Gene Program Summary
Program Clusters Mean Score Max Score Genes Used
B_plasma 22 0.9258 3.2133 8
T_NK_cytotoxic 22 0.2275 1.2177 10
Fibroblast_stroma 22 0.1745 2.1763 8
Myeloid_APC 22 0.1478 1.0388 9
Epithelial_tumor 22 0.1447 1.68 8
Checkpoint_exhaustion 22 0.1146 0.4071 8
Endothelial 22 0.1047 1.1217 7
Proliferation 22 0.1032 0.8088 7
Cluster QC
Cluster Cells Mean UMI Median Genes Mean Mito %
cluster_1 207 4334.2754 1541 3.0996
cluster_2 198 3997.2071 1605.5 2.6175
cluster_3 186 5137.6183 1998 3.1346
cluster_4 183 4824.4317 1796 2.7968
cluster_5 162 11806.6914 4178 4.7288
cluster_6 145 4497.3241 1515 4.2773
cluster_7 140 4763.6786 1748 3.4427
cluster_8 133 22725.3459 2004 1.2356
cluster_9 128 6318.4922 1533 2.9181
cluster_10 105 8455.2952 1876 1.389
cluster_11 91 10361.4176 3034 3.5257
cluster_12 88 1112.3068 350 0.9475
cluster_13 47 3805.1064 1824 6.8133
cluster_14 38 10408.3684 3072 3.3801
cluster_15 36 7463.3889 2666.5 4.0197
cluster_16 30 30266.6333 2140 0.7202
cluster_17 21 4510 1638 3.3266
cluster_18 17 4749.0588 2203 2.8857
cluster_19 14 22625.5 2114.5 1.2295
cluster_20 13 20450.0769 2532 1.0993
cluster_21 12 22329.6667 2194 0.696
cluster_22 4 11630.5 2168.5 1.8092
Top Cluster Marker Genes
Cluster Rank Gene Score Mean Expr Detect Fraction
cluster_21 1 IGKV3-15 8.8765 9.2364 1
cluster_20 1 IGLV1-44 8.8183 8.8948 1
cluster_22 1 IGHV1-69 7.9199 7.9556 1
cluster_19 1 IGLV1-47 7.6608 7.7726 1
cluster_16 1 IGLC2 4.8171 4.922 0.9667
cluster_8 1 IGHG1 4.7264 5.01 0.9398
cluster_11 1 COL1A1 3.4854 3.551 0.9231
cluster_10 1 KRT17 3.439 3.7344 0.9524
cluster_17 1 TPSAB1 3.4354 3.4354 1
cluster_15 1 IGFBP7 3.341 3.6362 0.9167
cluster_5 1 CXCL14 3.2841 3.3311 0.9074
cluster_18 1 CRYAB 2.9736 3.2282 0.9412
cluster_12 1 CXCL8 2.9602 3.2221 0.9886
cluster_6 1 HLA-DRA 2.9507 3.4896 0.9862
cluster_13 1 IGFBP7 2.9128 3.1997 1
cluster_14 1 CD74 2.495 4.2684 1
cluster_9 1 IL1B 2.1278 2.2431 0.7344
cluster_3 1 IL32 2.1081 3.0262 0.9839
cluster_2 1 CCL5 2.0191 2.3941 0.9596
cluster_7 1 GNLY 1.9958 2.1249 0.6929
cluster_4 1 CD3E 1.2776 1.8996 0.9727
cluster_1 1 IL7R 1.0005 1.3582 0.7826
cluster_19 2 IGHV4-31 7.0658 7.092 1
cluster_21 2 IGHV1-2 7.0612 7.1471 1
cluster_22 2 IGKV1-12 6.0873 6.0937 1
cluster_20 2 IGHV3-64 5.736 5.7612 1
cluster_16 2 IGHG1 4.7191 5.2464 0.9667
cluster_8 2 IGKC 4.4305 4.5972 0.9023
cluster_11 2 COL1A2 3.3369 3.3743 0.9451
cluster_5 2 CD9 3.2003 3.5024 0.9753
cluster_17 2 TPSB2 3.1257 3.1257 1
cluster_10 2 KRT6A 2.9771 3.2026 0.9429
cluster_6 2 CD74 2.8237 4.4396 0.9931
cluster_15 2 TAGLN 2.7151 2.7729 0.9722
cluster_12 2 G0S2 2.6223 2.7771 0.9432
cluster_18 2 CLU 2.2933 2.3963 0.7647
cluster_14 2 HLA-DRA 2.2819 2.9915 0.8947
cluster_9 2 CXCL8 2.0584 2.3189 0.6953
cluster_13 2 HSPG2 2.0483 2.0829 0.8723
cluster_7 2 CCL5 1.8774 2.321 0.8714

Primary Metadata

Core de-identified metadata fields migrated from the ImmuneAging donor manifest.

Donor ID
ESCC-111-07-1A
Sample ID
ESCC-111-07-1A
Dataset
CancerSCEM 2.0
Cohort
CancerSCEM 2.0 Chinese subset; Esophageal Squamous Cell Carcinoma
Age / Age Group
Pan-cancer Chinese cohort, per-donor ages not in CancerSCEM metadata
Sex
Not reported in public CancerSCEM metadata
Health Status
Esophageal Squamous Cell Carcinoma; Tumour
Tissue / Cell Source
Tumour
Modality
scRNA-seq (10X Genomics)
Cell Count
4,480
Analysis Status
Matrix available; UMAP generated
UMAP Status
Ready
Metadata / Source Notes
Project ID: ESCC-111; Cancer type: Esophageal Squamous Cell Carcinoma; Source: NCBI (GEO); Accession: GSE160269; Country: CHN; Sample type: Tumour; Protocol: 10X Genomics; Matrix: ESCC-111-07-1A.counts.matrix.tsv.gz (10.56 MB); UMAP: Scanpy-generated donor-level UMAP preview; cells=4480; raw genes=23818; Leiden clusters=22; coordinates TSV and summary JSON are available online.; Age/sex not reported in public CancerSCEM metadata. Age source: CancerSCEM 2.0 database; 400 samples across 47 cancer types; donor-level age not included in download.csv

Additional Clinical / Source Fields

Supplementary source metadata retained from the migrated manifest where available.

cancer type
Esophageal Squamous Cell Carcinoma
cancer type short
ESCC
library count
1
library sample ids
ESCC-111-07-1A
source reference
CancerSCEM 2.0 metadata table; data source=NCBI (GEO); accession=GSE160269; downloaded 2026-07-06
data accession
GSE160269
project id
ESCC-111
sample type
Tumour
country
CHN
data source
NCBI (GEO)
accession no
GSE160269
construction protocol
10X Genomics
transcriptome profile
Yes
metabolic profile
Yes
matrix status
Matrix available
matrix file name
ESCC-111-07-1A.counts.matrix.tsv.gz
matrix file size bytes
11077233
matrix file size mb
10.56
matrix download url
http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_matrix/ESCC-111-07-1A.counts.matrix.tsv.gz
umap coordinates url
http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_umap/ESCC-111-07-1A.umap.tsv.gz
umap summary url
http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_umap/ESCC-111-07-1A.summary.json
umap pipeline
Scanpy 1.9.8 normalize_total/log1p/HVG/PCA/neighbors/leiden/umap; cells=4480; raw_genes=23818; leiden_clusters=22; generated 2026-07-07
matrix integrity status
Gzip readable; UMAP generated