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ESCC-111-31-1A

De-identified Human Immune Atlas donor/sample detail for CancerSCEM 2.0. The record preserves available public metadata while avoiding direct identifiers.

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Donor-Level Analysis Results

Matrix-backed CancerSCEM donor analysis for ESCC-111-31-1A, generated 2026-07-09 12:54:49 +0800.

2,000Cells analyzed
22Clusters
23,053Expressed genes
5034Mean UMI
1787Mean genes
4.179Mean mito %
Donor-level analysis panel
Cluster cell counts, cluster-by-program score heatmap, and top marker genes.
CancerSCEM Deep Analysis Donor JSON UMAP Coordinates UMAP Summary
Gene Program Summary
Program Clusters Mean Score Max Score Genes Used
B_plasma 22 0.4584 2.3425 8
Epithelial_tumor 22 0.2697 1.7505 8
Myeloid_APC 22 0.2404 1.2032 9
T_NK_cytotoxic 22 0.2338 1.3188 10
Checkpoint_exhaustion 22 0.1675 0.6414 8
Endothelial 22 0.1236 1.2524 7
Fibroblast_stroma 22 0.1222 1.6466 8
Proliferation 22 0.1069 0.5798 7
Cluster QC
Cluster Cells Mean UMI Median Genes Mean Mito %
cluster_1 241 3488.6058 1348 4.1141
cluster_2 239 4442.749 1560 4.5349
cluster_3 187 2754.0642 1324 3.1213
cluster_4 173 4814.6012 1929 3.8727
cluster_5 159 3577.8616 1492 4.1743
cluster_6 147 8631.2721 2630 3.2184
cluster_7 146 5244.1164 1798 4.8333
cluster_8 110 7391.7727 2538 6.7748
cluster_9 107 7284.8879 1728 3.3199
cluster_10 82 3919.6829 1711 4.2738
cluster_11 70 5440.0714 2013 4.9631
cluster_12 59 3158.678 1467 4.4318
cluster_13 57 3517.5965 1452 4.4646
cluster_14 54 1685.7778 961.5 5.1689
cluster_15 40 20719.3 2250 1.7366
cluster_16 39 7525.4359 1808 2.4534
cluster_17 24 2401.7917 1052 3.8188
cluster_18 20 3200.65 1521.5 4.9478
cluster_19 15 6766.3333 2146 4.7023
cluster_20 11 2831 1314 4.3534
cluster_21 10 3853 1616 6.1283
cluster_22 10 2569.5 1467.5 5.8591
Top Cluster Marker Genes
Cluster Rank Gene Score Mean Expr Detect Fraction
cluster_19 1 DCN 4.1514 4.1638 1
cluster_9 1 S100A9 3.5237 3.9296 0.8598
cluster_15 1 SSR4 3.4642 4.0601 0.975
cluster_11 1 IGFBP7 3.135 3.2798 1
cluster_22 1 IGFBP7 3.0626 3.3019 1
cluster_20 1 TPSAB1 2.8278 2.8316 1
cluster_6 1 CD74 2.7724 4.7855 1
cluster_21 1 CCL5 2.7611 2.9421 1
cluster_8 1 KRT19 2.758 3.3269 0.9636
cluster_18 1 BACH2 2.724 3.3743 1
cluster_7 1 KRT17 2.6858 3.1897 0.9726
cluster_16 1 PLAUR 2.5259 2.6654 0.9231
cluster_2 1 CD74 2.3999 4.33 1
cluster_1 1 CD74 2.3823 4.3121 1
cluster_13 1 NKG7 2.3092 2.4149 0.9825
cluster_4 1 CD7 2.2751 2.5384 0.9769
cluster_10 1 CCL5 2.2722 2.3739 0.9756
cluster_17 1 FYN 2.0277 2.3987 1
cluster_14 1 SIPA1L1 1.7212 2.2275 0.9815
cluster_12 1 IFITM3 1.6705 2.2818 0.8983
cluster_5 1 SRGN 1.6508 2.5866 0.9623
cluster_3 1 S100A9 1.5111 1.9642 0.7807
cluster_15 2 JCHAIN 3.2723 3.3487 0.85
cluster_9 2 S100A8 3.2063 3.5164 0.8318
cluster_19 2 FBLN1 3.1635 3.1906 0.9333
cluster_11 2 SPARCL1 2.9276 3.0307 0.9571
cluster_18 2 LPP 2.7179 3.284 1
cluster_21 2 CD7 2.4388 2.8867 1
cluster_8 2 KRT5 2.3949 2.9097 0.9727
cluster_16 2 IFI30 2.3892 2.7476 0.7949
cluster_20 2 VIM 2.3412 3.1195 0.9091
cluster_22 2 TAGLN 2.3376 2.3606 0.9
cluster_6 2 HLA-DRA 2.2861 3.4537 0.9932
cluster_13 2 CCL5 2.2287 2.36 0.9474
cluster_1 2 HLA-DRA 2.189 3.2608 1
cluster_10 2 CD7 2.1244 2.4974 0.9878
cluster_2 2 HLA-DRA 2.099 3.1838 0.9958
cluster_7 2 KRT19 1.8596 2.4444 0.9658
cluster_4 2 CD3E 1.8448 2.1149 0.9827
cluster_14 2 BACH2 1.7034 2.3349 0.9259

Primary Metadata

Core de-identified metadata fields migrated from the ImmuneAging donor manifest.

Donor ID
ESCC-111-31-1A
Sample ID
ESCC-111-31-1A
Dataset
CancerSCEM 2.0
Cohort
CancerSCEM 2.0 Chinese subset; Esophageal Squamous Cell Carcinoma
Age / Age Group
Pan-cancer Chinese cohort, per-donor ages not in CancerSCEM metadata
Sex
Not reported in public CancerSCEM metadata
Health Status
Esophageal Squamous Cell Carcinoma; Tumour
Tissue / Cell Source
Tumour
Modality
scRNA-seq (10X Genomics)
Cell Count
4,064
Analysis Status
Matrix available; UMAP generated
UMAP Status
Ready
Metadata / Source Notes
Project ID: ESCC-111; Cancer type: Esophageal Squamous Cell Carcinoma; Source: NCBI (GEO); Accession: GSE160269; Country: CHN; Sample type: Tumour; Protocol: 10X Genomics; Matrix: ESCC-111-31-1A.counts.matrix.tsv.gz (8.90 MB); UMAP: Scanpy-generated donor-level UMAP preview; cells=4064; raw genes=23925; Leiden clusters=22; coordinates TSV and summary JSON are available online.; Age/sex not reported in public CancerSCEM metadata. Age source: CancerSCEM 2.0 database; 400 samples across 47 cancer types; donor-level age not included in download.csv

Additional Clinical / Source Fields

Supplementary source metadata retained from the migrated manifest where available.

cancer type
Esophageal Squamous Cell Carcinoma
cancer type short
ESCC
library count
1
library sample ids
ESCC-111-31-1A
source reference
CancerSCEM 2.0 metadata table; data source=NCBI (GEO); accession=GSE160269; downloaded 2026-07-06
data accession
GSE160269
project id
ESCC-111
sample type
Tumour
country
CHN
data source
NCBI (GEO)
accession no
GSE160269
construction protocol
10X Genomics
transcriptome profile
Yes
metabolic profile
Yes
matrix status
Matrix available
matrix file name
ESCC-111-31-1A.counts.matrix.tsv.gz
matrix file size bytes
9334440
matrix file size mb
8.90
matrix download url
http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_matrix/ESCC-111-31-1A.counts.matrix.tsv.gz
umap coordinates url
http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_umap/ESCC-111-31-1A.umap.tsv.gz
umap summary url
http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_umap/ESCC-111-31-1A.summary.json
umap pipeline
Scanpy 1.9.8 normalize_total/log1p/HVG/PCA/neighbors/leiden/umap; cells=4064; raw_genes=23925; leiden_clusters=22; generated 2026-07-07
matrix integrity status
Gzip readable; UMAP generated