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PTC-069-03-1A

De-identified Human Immune Atlas donor/sample detail for CancerSCEM 2.0. The record preserves available public metadata while avoiding direct identifiers.

Donor-Level Analysis Results

Matrix-backed CancerSCEM donor analysis for PTC-069-03-1A, generated 2026-07-09 12:54:49 +0800.

2,000Cells analyzed
18Clusters
24,668Expressed genes
7823Mean UMI
2684Mean genes
4.503Mean mito %
Donor-level analysis panel
Cluster cell counts, cluster-by-program score heatmap, and top marker genes.
Gene Program Summary
Program Clusters Mean Score Max Score Genes Used
B_plasma 18 0.3927 2.1815 8
T_NK_cytotoxic 18 0.3616 1.5385 10
Fibroblast_stroma 18 0.3284 2.3597 8
Myeloid_APC 18 0.2499 1.6959 9
Checkpoint_exhaustion 18 0.2171 0.8717 8
Endothelial 18 0.1386 1.3265 7
Epithelial_tumor 18 0.0948 0.5955 7
Proliferation 18 0.0723 0.2259 7
Cluster QC
Cluster Cells Mean UMI Median Genes Mean Mito %
cluster_1 303 7994.9571 2848 4.9845
cluster_2 278 9260.8129 3096 4.7068
cluster_3 272 7579.1397 2822.5 5.0096
cluster_4 270 8257.3185 2891 4.6077
cluster_5 153 6726.4967 2616 4.7604
cluster_6 112 6416.1429 2821 4.4183
cluster_7 108 4107.3611 1105.5 2.5339
cluster_8 88 8231.0795 2955 3.8992
cluster_9 73 6040.5342 2326 4.6037
cluster_10 64 10670.4844 3530 4.8904
cluster_11 62 8850.6935 3268.5 5.5964
cluster_12 49 10137.1633 3288 4.277
cluster_13 40 12099.85 3617.5 4.0596
cluster_14 39 859.3846 435 3.8309
cluster_15 38 4494.2632 1532.5 0.3148
cluster_16 23 16017.3913 373 1.7787
cluster_18 14 6716.2143 2292 7.8307
cluster_17 14 8735.3571 2955.5 4.3263
Top Cluster Marker Genes
Cluster Rank Gene Score Mean Expr Detect Fraction
cluster_16 1 IGHG3 5.9798 6.1436 1
cluster_18 1 TPSB2 4.1502 4.1527 1
cluster_10 1 MGP 4.112 4.7605 0.9844
cluster_12 1 HLA-DRA 3.6756 4.123 1
cluster_11 1 TAGLN 3.5245 3.824 0.9677
cluster_5 1 IGFBP7 3.0304 3.7382 0.9804
cluster_17 1 BANK1 2.9186 2.9305 1
cluster_3 1 GNLY 2.7449 2.9376 0.9375
cluster_13 1 IFI30 2.4744 2.591 0.825
cluster_8 1 CXCL13 2.3157 2.4031 0.8977
cluster_6 1 IGFBP7 2.2399 3.0541 0.9554
cluster_2 1 CCL5 2.1852 3.1089 0.9784
cluster_15 1 TSC22D1 2.0459 2.5448 0.9474
cluster_7 1 CLU 1.7863 2.3096 0.9259
cluster_1 1 BATF 1.7569 2.089 0.9472
cluster_4 1 CXCR4 1.1883 2.9399 0.9519
cluster_9 1 CCL5 1.1318 2.3179 0.9178
cluster_14 1 CXCL14 0.4826 0.5869 0.359
cluster_16 2 IGKC 5.6957 6.1036 1
cluster_10 2 IGFBP7 3.7145 4.5352 0.9844
cluster_18 2 TPSAB1 3.5289 3.5296 1
cluster_11 2 IGFBP7 3.4435 4.2763 1
cluster_12 2 CD74 3.1484 4.149 1
cluster_5 2 RGS5 2.9308 3.1716 0.9281
cluster_17 2 HLA-DRA 2.7138 3.2322 1
cluster_3 2 NKG7 2.4161 3.0357 0.9816
cluster_13 2 HLA-DRA 2.3214 2.8124 0.925
cluster_6 2 PLVAP 2.2029 2.2404 0.9286
cluster_15 2 S100A13 1.9232 2.1238 0.9737
cluster_2 2 CCL4 1.7992 2.8993 0.9568
cluster_1 2 RGS1 1.7265 2.7988 0.9571
cluster_7 2 FN1 1.5816 2.1952 0.9074
cluster_8 2 TOX 1.539 2.2822 1
cluster_4 2 ATP1B3 1.0966 2.6074 0.9111
cluster_9 2 JUN 0.8817 3.0254 0.9726
cluster_14 2 C3 0.4535 0.5343 0.5128
cluster_16 3 IGHG1 5.1963 5.2561 0.9565
cluster_10 3 APOE 3.6851 4.2881 0.9844
cluster_12 3 C1QA 3.1158 3.1741 0.9796
cluster_11 3 ACTA2 3.0988 3.3497 0.9677

Primary Metadata

Core de-identified metadata fields migrated from the ImmuneAging donor manifest.

Donor ID
PTC-069-03-1A
Sample ID
PTC-069-03-1A
Dataset
CancerSCEM 2.0
Cohort
CancerSCEM 2.0 Chinese subset; Papillary Thyroid Carcinoma
Age / Age Group
Pan-cancer Chinese cohort, per-donor ages not in CancerSCEM metadata
Sex
Not reported in public CancerSCEM metadata
Health Status
Papillary Thyroid Carcinoma; Tumour
Tissue / Cell Source
Tumour
Modality
scRNA-seq (10X Genomics)
Cell Count
2,831
Analysis Status
Matrix available; UMAP generated
UMAP Status
Ready
Metadata / Source Notes
Project ID: PTC-069; Cancer type: Papillary Thyroid Carcinoma; Source: NCBI (GEO); Accession: GSE191288; Country: CHN; Sample type: Tumour; Protocol: 10X Genomics; Matrix: PTC-069-03-1A.counts.matrix.tsv.gz (8.56 MB); UMAP: Scanpy-generated donor-level UMAP preview; cells=2831; raw genes=26272; Leiden clusters=18; coordinates TSV and summary JSON are available online.; Age/sex not reported in public CancerSCEM metadata. Age source: CancerSCEM 2.0 database; 400 samples across 47 cancer types; donor-level age not included in download.csv

Additional Clinical / Source Fields

Supplementary source metadata retained from the migrated manifest where available.

cancer type
Papillary Thyroid Carcinoma
cancer type short
PTC
library count
1
library sample ids
PTC-069-03-1A
source reference
CancerSCEM 2.0 metadata table; data source=NCBI (GEO); accession=GSE191288; downloaded 2026-07-06
data accession
GSE191288
project id
PTC-069
sample type
Tumour
country
CHN
data source
NCBI (GEO)
accession no
GSE191288
construction protocol
10X Genomics
transcriptome profile
Yes
metabolic profile
Yes
matrix status
Matrix available
matrix file name
PTC-069-03-1A.counts.matrix.tsv.gz
matrix file size bytes
8977933
matrix file size mb
8.56
matrix download url
umap coordinates url
umap summary url
umap pipeline
Scanpy 1.9.8 normalize_total/log1p/HVG/PCA/neighbors/leiden/umap; cells=2831; raw_genes=26272; leiden_clusters=18; generated 2026-07-07
matrix integrity status
Gzip readable; UMAP generated