RY4221

MTBLS5568 • Plasma LC-MS metabolomics • Prediabetes whey-protein intervention

◂ Prev All Next ▸
Female Sex
54 yr Age
27.6 BMI
4% MRI Pancreas Fat
30 Total Samples (30 POS + 0 NEG)
5 Timepoints: 0, 30, 60, 120, 240 min

Top 15 Metabolite Features (Across All Samples)

L-Leucine

Formula: C6H13NO2 • m/z: 130.0869 • RT: 599.4486
HMDB: HMDB00687 • KEGG: C00123 • Found: 30×
Total abundance
221,528,101

L-Glutamic Acid

Formula: C5H9NO4 • m/z: 146.04542 • RT: 796.2
HMDB: HMDB00148 • KEGG: C00025 • Found: 30×
Total abundance
58,134,964

Pyridoxamine dihydrochloride

Formula: C8H14Cl2N2O2 • m/z: 133.08047 • RT: 741.336 • Found: 30×
Total abundance
16,428,074

L-Tyrosine

Formula: C9H11NO3 • m/z: 180.06659 • RT: 700.038
HMDB: HMDB00158 • KEGG: C00082 • Found: 30×
Total abundance
15,843,709

Methionine sulfoxide

Formula: C5H11NO3S • m/z: 164.03856 • RT: 769.768
HMDB: HMDB02005 • KEGG: C02989 • Found: 30×
Total abundance
15,531,253

Citrulline

Formula: C6H13N3O3 • m/z: 174.08819 • RT: 834.04
HMDB: HMDB00904 • KEGG: C00327 • Found: 30×
Total abundance
14,878,234

L-Isoleucine

Formula: C6H13NO2 • m/z: 133.10592 • RT: 589.6156
HMDB: HMDB00172 • KEGG: C00407 • Found: 30×
Total abundance
13,515,399

N-Acetylserine

Formula: C5H9NO4 • m/z: 148.06085 • RT: 790.658
HMDB: HMDB02931 • Found: 28×
Total abundance
12,118,897

L-Serine

Formula: C3H7NO3 • m/z: 104.03466 • RT: 826.138
HMDB: HMDB00187 • KEGG: C00065 • Found: 28×
Total abundance
10,775,200

L-Asparagine

Formula: C4H8N2O3 • m/z: 131.04572 • RT: 821.266
HMDB: HMDB00168 • KEGG: C00152 • Found: 20×
Total abundance
5,733,776

Leucine

Formula: C6H13NO2 • m/z: 133.10591 • RT: 603.562
HMDB: HMDB00687 • KEGG: C00123 • Found: 6×
Total abundance
3,640,850

L-2-Aminoadipic acid

Formula: C6H11NO4 • m/z: 162.07635 • RT: 756.777
HMDB: HMDB00510 • KEGG: C00956 • Found: 4×
Total abundance
2,280,859

L-Methionine

Formula: C5H11NO2S • m/z: 148.04348 • RT: 640.282
HMDB: HMDB00696 • KEGG: C00073 • Found: 4×
Total abundance
1,243,323

Sample Timecourse (30 samples)

WPI Dose: 50 g

Time (min)ModeSource NameBatch #1 MetaboliteAbundance #2 MetaboliteAbundance #3 MetaboliteAbundance
0 POS 20180205_TOFI2_B2_HILIC_029 2 L-Leucine 5,262,678 L-Glutamic Acid 1,786,079 Pyridoxamine dihydrochloride 751,413
0 POS 20180205_TOFI2_B2_HILIC_029 2 L-Leucine 5,262,678 L-Glutamic Acid 1,786,079 Pyridoxamine dihydrochloride 751,413
30 POS 20180205_TOFI2_B2_HILIC_030 2 L-Leucine 9,731,970 L-Glutamic Acid 1,887,247 Pyridoxamine dihydrochloride 795,655
30 POS 20180205_TOFI2_B2_HILIC_030 2 L-Leucine 9,731,970 L-Glutamic Acid 1,887,247 Pyridoxamine dihydrochloride 795,655
60 POS 20180205_TOFI2_B2_HILIC_031 2 L-Leucine 14,971,395 L-Glutamic Acid 2,029,004 L-Tyrosine 988,610
60 POS 20180205_TOFI2_B2_HILIC_031 2 L-Leucine 14,971,395 L-Glutamic Acid 2,029,004 L-Tyrosine 988,610
120 POS 20180205_TOFI2_B2_HILIC_032 2 L-Leucine 21,209,106 L-Glutamic Acid 2,073,393 L-Isoleucine 1,368,772
120 POS 20180205_TOFI2_B2_HILIC_032 2 L-Leucine 21,209,106 L-Glutamic Acid 2,073,393 L-Isoleucine 1,368,772
240 POS 20180205_TOFI2_B2_HILIC_033 2 L-Leucine 7,887,233 L-Glutamic Acid 1,745,992 Pyridoxamine dihydrochloride 664,720
240 POS 20180205_TOFI2_B2_HILIC_033 2 L-Leucine 7,887,233 L-Glutamic Acid 1,745,992 Pyridoxamine dihydrochloride 664,720

WPI Dose: 0 g

Time (min)ModeSource NameBatch #1 MetaboliteAbundance #2 MetaboliteAbundance #3 MetaboliteAbundance
0 POS 20180205_TOFI2_B2_HILIC_035 2 L-Leucine 3,666,118 L-Glutamic Acid 1,877,570 Methionine sulfoxide 582,417
0 POS 20180205_TOFI2_B2_HILIC_035 2 L-Leucine 3,666,118 L-Glutamic Acid 1,877,570 Methionine sulfoxide 582,417
30 POS 20180205_TOFI2_B2_HILIC_036 2 L-Leucine 3,801,452 L-Glutamic Acid 1,943,823 Methionine sulfoxide 564,923
30 POS 20180205_TOFI2_B2_HILIC_036 2 L-Leucine 3,801,452 L-Glutamic Acid 1,943,823 Methionine sulfoxide 564,923
60 POS 20180205_TOFI2_B2_HILIC_037 2 L-Leucine 3,761,402 L-Glutamic Acid 1,937,978 Methionine sulfoxide 481,479
60 POS 20180205_TOFI2_B2_HILIC_037 2 L-Leucine 3,761,402 L-Glutamic Acid 1,937,978 Methionine sulfoxide 481,479
120 POS 20180205_TOFI2_B2_HILIC_038 2 L-Leucine 3,725,940 L-Glutamic Acid 2,049,224 Methionine sulfoxide 438,339
120 POS 20180205_TOFI2_B2_HILIC_038 2 L-Leucine 3,725,940 L-Glutamic Acid 2,049,224 Methionine sulfoxide 438,339
240 POS 20180205_TOFI2_B2_HILIC_039 2 L-Leucine 4,742,076 L-Glutamic Acid 2,023,566 L-Serine 404,714
240 POS 20180205_TOFI2_B2_HILIC_039 2 L-Leucine 4,742,076 L-Glutamic Acid 2,023,566 L-Serine 404,714

WPI Dose: 12.5 g

Time (min)ModeSource NameBatch #1 MetaboliteAbundance #2 MetaboliteAbundance #3 MetaboliteAbundance
0 POS 20180205_TOFI2_B2_HILIC_040 2 L-Leucine 3,981,856 L-Glutamic Acid 1,872,608 Pyridoxamine dihydrochloride 431,053
0 POS 20180205_TOFI2_B2_HILIC_040 2 L-Leucine 3,981,856 L-Glutamic Acid 1,872,608 Pyridoxamine dihydrochloride 431,053
30 POS 20180205_TOFI2_B2_HILIC_041 2 L-Leucine 8,941,712 L-Glutamic Acid 2,193,916 Methionine sulfoxide 649,757
30 POS 20180205_TOFI2_B2_HILIC_041 2 L-Leucine 8,941,712 L-Glutamic Acid 2,193,916 Methionine sulfoxide 649,757
60 POS 20180205_TOFI2_B2_HILIC_042 2 L-Leucine 9,631,668 L-Glutamic Acid 2,071,882 L-Tyrosine 585,418
60 POS 20180205_TOFI2_B2_HILIC_042 2 L-Leucine 9,631,668 L-Glutamic Acid 2,071,882 L-Tyrosine 585,418
120 POS 20180205_TOFI2_B2_HILIC_043 2 L-Leucine 5,284,214 L-Glutamic Acid 1,739,954 Pyridoxamine dihydrochloride 445,126
120 POS 20180205_TOFI2_B2_HILIC_043 2 L-Leucine 5,284,214 L-Glutamic Acid 1,739,954 Pyridoxamine dihydrochloride 445,126
240 POS 20180205_TOFI2_B2_HILIC_044 2 L-Leucine 4,165,228 L-Glutamic Acid 1,835,245 L-Serine 369,888
240 POS 20180205_TOFI2_B2_HILIC_044 2 L-Leucine 4,165,228 L-Glutamic Acid 1,835,245 L-Serine 369,888

All Samples

20180205_TOFI2_B2_HILIC_029 POS

Time: 0 min • Dose: 50 g • Batch: 2
L-Leucine 5,262,678
L-Glutamic Acid 1,786,079
Pyridoxamine dihydrochloride 751,413
Citrulline 616,859
L-Tyrosine 558,107

20180205_TOFI2_B2_HILIC_029 POS

Time: 0 min • Dose: 50 g • Batch: 2
L-Leucine 5,262,678
L-Glutamic Acid 1,786,079
Pyridoxamine dihydrochloride 751,413
Citrulline 616,859
L-Tyrosine 558,107

20180205_TOFI2_B2_HILIC_035 POS

Time: 0 min • Dose: 0 g • Batch: 2
L-Leucine 3,666,118
L-Glutamic Acid 1,877,570
Methionine sulfoxide 582,417
N-Acetylserine 509,345
Pyridoxamine dihydrochloride 481,756

20180205_TOFI2_B2_HILIC_035 POS

Time: 0 min • Dose: 0 g • Batch: 2
L-Leucine 3,666,118
L-Glutamic Acid 1,877,570
Methionine sulfoxide 582,417
N-Acetylserine 509,345
Pyridoxamine dihydrochloride 481,756

20180205_TOFI2_B2_HILIC_040 POS

Time: 0 min • Dose: 12.5 g • Batch: 2
L-Leucine 3,981,856
L-Glutamic Acid 1,872,608
Pyridoxamine dihydrochloride 431,053
N-Acetylserine 416,820
L-Serine 382,500

20180205_TOFI2_B2_HILIC_040 POS

Time: 0 min • Dose: 12.5 g • Batch: 2
L-Leucine 3,981,856
L-Glutamic Acid 1,872,608
Pyridoxamine dihydrochloride 431,053
N-Acetylserine 416,820
L-Serine 382,500

20180205_TOFI2_B2_HILIC_030 POS

Time: 30 min • Dose: 50 g • Batch: 2
L-Leucine 9,731,970
L-Glutamic Acid 1,887,247
Pyridoxamine dihydrochloride 795,655
L-Tyrosine 763,127
Methionine sulfoxide 717,334

20180205_TOFI2_B2_HILIC_030 POS

Time: 30 min • Dose: 50 g • Batch: 2
L-Leucine 9,731,970
L-Glutamic Acid 1,887,247
Pyridoxamine dihydrochloride 795,655
L-Tyrosine 763,127
Methionine sulfoxide 717,334

20180205_TOFI2_B2_HILIC_036 POS

Time: 30 min • Dose: 0 g • Batch: 2
L-Leucine 3,801,452
L-Glutamic Acid 1,943,823
Methionine sulfoxide 564,923
Pyridoxamine dihydrochloride 434,211
L-Tyrosine 360,005

20180205_TOFI2_B2_HILIC_036 POS

Time: 30 min • Dose: 0 g • Batch: 2
L-Leucine 3,801,452
L-Glutamic Acid 1,943,823
Methionine sulfoxide 564,923
Pyridoxamine dihydrochloride 434,211
L-Tyrosine 360,005

20180205_TOFI2_B2_HILIC_041 POS

Time: 30 min • Dose: 12.5 g • Batch: 2
L-Leucine 8,941,712
L-Glutamic Acid 2,193,916
Methionine sulfoxide 649,757
L-Tyrosine 615,671
Pyridoxamine dihydrochloride 582,604

20180205_TOFI2_B2_HILIC_041 POS

Time: 30 min • Dose: 12.5 g • Batch: 2
L-Leucine 8,941,712
L-Glutamic Acid 2,193,916
Methionine sulfoxide 649,757
L-Tyrosine 615,671
Pyridoxamine dihydrochloride 582,604

20180205_TOFI2_B2_HILIC_031 POS

Time: 60 min • Dose: 50 g • Batch: 2
L-Leucine 14,971,395
L-Glutamic Acid 2,029,004
L-Tyrosine 988,610
L-Isoleucine 939,423
Methionine sulfoxide 842,940

20180205_TOFI2_B2_HILIC_031 POS

Time: 60 min • Dose: 50 g • Batch: 2
L-Leucine 14,971,395
L-Glutamic Acid 2,029,004
L-Tyrosine 988,610
L-Isoleucine 939,423
Methionine sulfoxide 842,940

20180205_TOFI2_B2_HILIC_037 POS

Time: 60 min • Dose: 0 g • Batch: 2
L-Leucine 3,761,402
L-Glutamic Acid 1,937,978
Methionine sulfoxide 481,479
Pyridoxamine dihydrochloride 403,462
L-Serine 370,776

20180205_TOFI2_B2_HILIC_037 POS

Time: 60 min • Dose: 0 g • Batch: 2
L-Leucine 3,761,402
L-Glutamic Acid 1,937,978
Methionine sulfoxide 481,479
Pyridoxamine dihydrochloride 403,462
L-Serine 370,776

20180205_TOFI2_B2_HILIC_042 POS

Time: 60 min • Dose: 12.5 g • Batch: 2
L-Leucine 9,631,668
L-Glutamic Acid 2,071,882
L-Tyrosine 585,418
L-Isoleucine 584,351
Citrulline 571,235

20180205_TOFI2_B2_HILIC_042 POS

Time: 60 min • Dose: 12.5 g • Batch: 2
L-Leucine 9,631,668
L-Glutamic Acid 2,071,882
L-Tyrosine 585,418
L-Isoleucine 584,351
Citrulline 571,235

20180205_TOFI2_B2_HILIC_032 POS

Time: 120 min • Dose: 50 g • Batch: 2
L-Leucine 21,209,106
L-Glutamic Acid 2,073,393
L-Isoleucine 1,368,772
Citrulline 1,255,486
L-Tyrosine 1,192,411

20180205_TOFI2_B2_HILIC_032 POS

Time: 120 min • Dose: 50 g • Batch: 2
L-Leucine 21,209,106
L-Glutamic Acid 2,073,393
L-Isoleucine 1,368,772
Citrulline 1,255,486
L-Tyrosine 1,192,411

20180205_TOFI2_B2_HILIC_038 POS

Time: 120 min • Dose: 0 g • Batch: 2
L-Leucine 3,725,940
L-Glutamic Acid 2,049,224
Methionine sulfoxide 438,339
Pyridoxamine dihydrochloride 391,177
L-Serine 391,128

20180205_TOFI2_B2_HILIC_038 POS

Time: 120 min • Dose: 0 g • Batch: 2
L-Leucine 3,725,940
L-Glutamic Acid 2,049,224
Methionine sulfoxide 438,339
Pyridoxamine dihydrochloride 391,177
L-Serine 391,128

20180205_TOFI2_B2_HILIC_043 POS

Time: 120 min • Dose: 12.5 g • Batch: 2
L-Leucine 5,284,214
L-Glutamic Acid 1,739,954
Pyridoxamine dihydrochloride 445,126
Citrulline 382,697
L-Tyrosine 382,203

20180205_TOFI2_B2_HILIC_043 POS

Time: 120 min • Dose: 12.5 g • Batch: 2
L-Leucine 5,284,214
L-Glutamic Acid 1,739,954
Pyridoxamine dihydrochloride 445,126
Citrulline 382,697
L-Tyrosine 382,203

20180205_TOFI2_B2_HILIC_033 POS

Time: 240 min • Dose: 50 g • Batch: 2
L-Leucine 7,887,233
L-Glutamic Acid 1,745,992
Pyridoxamine dihydrochloride 664,720
Citrulline 619,282
L-Isoleucine 485,190

20180205_TOFI2_B2_HILIC_033 POS

Time: 240 min • Dose: 50 g • Batch: 2
L-Leucine 7,887,233
L-Glutamic Acid 1,745,992
Pyridoxamine dihydrochloride 664,720
Citrulline 619,282
L-Isoleucine 485,190

20180205_TOFI2_B2_HILIC_039 POS

Time: 240 min • Dose: 0 g • Batch: 2
L-Leucine 4,742,076
L-Glutamic Acid 2,023,566
L-Serine 404,714
Pyridoxamine dihydrochloride 404,353
Methionine sulfoxide 351,032

20180205_TOFI2_B2_HILIC_039 POS

Time: 240 min • Dose: 0 g • Batch: 2
L-Leucine 4,742,076
L-Glutamic Acid 2,023,566
L-Serine 404,714
Pyridoxamine dihydrochloride 404,353
Methionine sulfoxide 351,032

20180205_TOFI2_B2_HILIC_044 POS

Time: 240 min • Dose: 12.5 g • Batch: 2
L-Leucine 4,165,228
L-Glutamic Acid 1,835,245
L-Serine 369,888
Pyridoxamine dihydrochloride 356,548
Citrulline 308,966

20180205_TOFI2_B2_HILIC_044 POS

Time: 240 min • Dose: 12.5 g • Batch: 2
L-Leucine 4,165,228
L-Glutamic Acid 1,835,245
L-Serine 369,888
Pyridoxamine dihydrochloride 356,548
Citrulline 308,966
◂ Previous Back to Donor List Next ▸