⚙ How is this computed? Methods: Cohort Data
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Aggregate-derived cohort evidence

Supercentenarian single-cell aging clock

Study-level participant index for the Longevity Cohort module. Open a tracking ID to inspect its de-identified group metadata, source scope, and data-access notes.

Tracking rows summarize published group counts; they do not identify individual donors.
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Cohort Seven supercentenarians + Shanghai reference cohort; Wuhan/Japan validation
Technology scRNA-seq + single-cell aging clock + ribosome-inhibition assay
Data access GSE213516 open; SC not local
GEO GSE213516 open (10/17 Shanghai reference processed); supercentenarian hum0229 not local
Aggregate-derived tracking Exact participant-level age, sex and sample accession are not mapped in the currently curated public metadata. These LACA tracking IDs are derived from published aggregate group counts. They are not original participant, donor, or biosample identifiers.
Open GEO analysis

GSE213516 processed samples

Local scanpy analysis of the public GEO processed matrices (10 of 17 Shanghai reference samples; 83,191 cells). Supercentenarian samples (hum0229) are not on this host. The aging score is a heuristic proxy, not the published clock.

10GEO samples on disk
83,191Cells in local object
10 / 17Shanghai reference coverage
hum0229Supercentenarian data not local
UMAP (Leiden 0.8)
UMAP (Leiden 0.8)Dataset-level embedding of the local GSE213516 processed object.
UMAP by GEO sample
UMAP by GEO sampleSame embedding coloured by the 10 public GEO sample codes.
Broad cell composition
Broad cell compositionPer-sample percentages for B, NK, monocytes and CD8 T (heuristic labels).
Heuristic aging score by sample
Heuristic aging score by sampleNot the published Supercentenarian clock. Higher = more aged/stressed signature in this object.
Heuristic aging score on UMAP
Heuristic aging score on UMAPCell-level heuristic score projected on the same UMAP.
Leiden marker dotplot
Leiden marker dotplotRanked markers for Leiden 0.8 clusters in the local processed object.
GEO sample GSM Sex / age code Cells Mean aging Flag B% NK% Mono% CD8T% Detail
F55 GSM6588517 Female / 55 8,948 0.903 high 6.4 0.0 2.1 0.0 View sample
F65 GSM6588520 Female / 65 7,715 0.250 medium 2.6 0.4 4.5 0.0 View sample
F60 GSM6588518 Female / 60 8,263 0.220 medium 4.2 0.2 2.9 0.0 View sample
F47 GSM6588513 Female / 47 7,831 0.168 medium 1.6 31.1 47.7 0.1 View sample
F66 GSM6588515 Female / 66 7,845 -0.074 medium 7.2 44.3 21.2 0.1 View sample
F40 GSM6588519 Female / 40 6,041 -0.106 medium 5.0 0.0 1.5 0.3 View sample
F36 GSM6588512 Female / 36 10,641 -0.143 medium 7.1 29.0 24.7 0.1 View sample
F58 GSM6588514 Female / 58 9,944 -0.177 medium 4.3 1.5 17.8 14.6 View sample
F77 GSM6588516 Female / 77 7,581 -0.442 low 3.1 9.9 21.2 0.3 View sample
F30 GSM6588511 Female / 30 8,382 -0.631 low 7.9 5.9 10.4 5.1 View sample
Cohort evidence index

Tracking Table

24 aggregate-derived tracking rows in this study; 50 rows per page.

CEN 7OFF 17CTRL 0Aggregate-derived · no identity encoded
Swipe horizontally to inspect all tracking fields →
Aggregate-derived cohort tracking rows with group, age scope, sex reporting, cohort source, material, and detail links.
Details
LC-37379396-SC-001
LACA tracking ID
 Supercentenarian Study-defined supercentenarian group; individual age unavailable Not reported at participant level Seven supercentenarians + Shanghai reference cohort; Wuhan/Japan validation Peripheral blood mononuclear cells (PBMC) View Detail
LC-37379396-SC-002
LACA tracking ID
 Supercentenarian Study-defined supercentenarian group; individual age unavailable Not reported at participant level Seven supercentenarians + Shanghai reference cohort; Wuhan/Japan validation Peripheral blood mononuclear cells (PBMC) View Detail
LC-37379396-SC-003
LACA tracking ID
 Supercentenarian Study-defined supercentenarian group; individual age unavailable Not reported at participant level Seven supercentenarians + Shanghai reference cohort; Wuhan/Japan validation Peripheral blood mononuclear cells (PBMC) View Detail
LC-37379396-SC-004
LACA tracking ID
 Supercentenarian Study-defined supercentenarian group; individual age unavailable Not reported at participant level Seven supercentenarians + Shanghai reference cohort; Wuhan/Japan validation Peripheral blood mononuclear cells (PBMC) View Detail
LC-37379396-SC-005
LACA tracking ID
 Supercentenarian Study-defined supercentenarian group; individual age unavailable Not reported at participant level Seven supercentenarians + Shanghai reference cohort; Wuhan/Japan validation Peripheral blood mononuclear cells (PBMC) View Detail
LC-37379396-SC-006
LACA tracking ID
 Supercentenarian Study-defined supercentenarian group; individual age unavailable Not reported at participant level Seven supercentenarians + Shanghai reference cohort; Wuhan/Japan validation Peripheral blood mononuclear cells (PBMC) View Detail
LC-37379396-SC-007
LACA tracking ID
 Supercentenarian Study-defined supercentenarian group; individual age unavailable Not reported at participant level Seven supercentenarians + Shanghai reference cohort; Wuhan/Japan validation Peripheral blood mononuclear cells (PBMC) View Detail
LC-37379396-CTL-001
LACA tracking ID
 Control / reference Published reference-group range: 28–77 years; individual age unavailable Not reported at participant level Seven supercentenarians + Shanghai reference cohort; Wuhan/Japan validation Peripheral blood mononuclear cells (PBMC) View Detail
LC-37379396-CTL-002
LACA tracking ID
 Control / reference Published reference-group range: 28–77 years; individual age unavailable Not reported at participant level Seven supercentenarians + Shanghai reference cohort; Wuhan/Japan validation Peripheral blood mononuclear cells (PBMC) View Detail
LC-37379396-CTL-003
LACA tracking ID
 Control / reference Published reference-group range: 28–77 years; individual age unavailable Not reported at participant level Seven supercentenarians + Shanghai reference cohort; Wuhan/Japan validation Peripheral blood mononuclear cells (PBMC) View Detail
LC-37379396-CTL-004
LACA tracking ID
 Control / reference Published reference-group range: 28–77 years; individual age unavailable Not reported at participant level Seven supercentenarians + Shanghai reference cohort; Wuhan/Japan validation Peripheral blood mononuclear cells (PBMC) View Detail
LC-37379396-CTL-005
LACA tracking ID
 Control / reference Published reference-group range: 28–77 years; individual age unavailable Not reported at participant level Seven supercentenarians + Shanghai reference cohort; Wuhan/Japan validation Peripheral blood mononuclear cells (PBMC) View Detail
LC-37379396-CTL-006
LACA tracking ID
 Control / reference Published reference-group range: 28–77 years; individual age unavailable Not reported at participant level Seven supercentenarians + Shanghai reference cohort; Wuhan/Japan validation Peripheral blood mononuclear cells (PBMC) View Detail
LC-37379396-CTL-007
LACA tracking ID
 Control / reference Published reference-group range: 28–77 years; individual age unavailable Not reported at participant level Seven supercentenarians + Shanghai reference cohort; Wuhan/Japan validation Peripheral blood mononuclear cells (PBMC) View Detail
LC-37379396-CTL-008
LACA tracking ID
 Control / reference Published reference-group range: 28–77 years; individual age unavailable Not reported at participant level Seven supercentenarians + Shanghai reference cohort; Wuhan/Japan validation Peripheral blood mononuclear cells (PBMC) View Detail
LC-37379396-CTL-009
LACA tracking ID
 Control / reference Published reference-group range: 28–77 years; individual age unavailable Not reported at participant level Seven supercentenarians + Shanghai reference cohort; Wuhan/Japan validation Peripheral blood mononuclear cells (PBMC) View Detail
LC-37379396-CTL-010
LACA tracking ID
 Control / reference Published reference-group range: 28–77 years; individual age unavailable Not reported at participant level Seven supercentenarians + Shanghai reference cohort; Wuhan/Japan validation Peripheral blood mononuclear cells (PBMC) View Detail
LC-37379396-CTL-011
LACA tracking ID
 Control / reference Published reference-group range: 28–77 years; individual age unavailable Not reported at participant level Seven supercentenarians + Shanghai reference cohort; Wuhan/Japan validation Peripheral blood mononuclear cells (PBMC) View Detail
LC-37379396-CTL-012
LACA tracking ID
 Control / reference Published reference-group range: 28–77 years; individual age unavailable Not reported at participant level Seven supercentenarians + Shanghai reference cohort; Wuhan/Japan validation Peripheral blood mononuclear cells (PBMC) View Detail
LC-37379396-CTL-013
LACA tracking ID
 Control / reference Published reference-group range: 28–77 years; individual age unavailable Not reported at participant level Seven supercentenarians + Shanghai reference cohort; Wuhan/Japan validation Peripheral blood mononuclear cells (PBMC) View Detail
LC-37379396-CTL-014
LACA tracking ID
 Control / reference Published reference-group range: 28–77 years; individual age unavailable Not reported at participant level Seven supercentenarians + Shanghai reference cohort; Wuhan/Japan validation Peripheral blood mononuclear cells (PBMC) View Detail
LC-37379396-CTL-015
LACA tracking ID
 Control / reference Published reference-group range: 28–77 years; individual age unavailable Not reported at participant level Seven supercentenarians + Shanghai reference cohort; Wuhan/Japan validation Peripheral blood mononuclear cells (PBMC) View Detail
LC-37379396-CTL-016
LACA tracking ID
 Control / reference Published reference-group range: 28–77 years; individual age unavailable Not reported at participant level Seven supercentenarians + Shanghai reference cohort; Wuhan/Japan validation Peripheral blood mononuclear cells (PBMC) View Detail
LC-37379396-CTL-017
LACA tracking ID
 Control / reference Published reference-group range: 28–77 years; individual age unavailable Not reported at participant level Seven supercentenarians + Shanghai reference cohort; Wuhan/Japan validation Peripheral blood mononuclear cells (PBMC) View Detail
Showing tracking rows