⚙ How is this computed? Methods: Cross-Species Comparison

Gene Longevity Correlation

Query the Spearman rank correlation between a gene's expression level and maximum lifespan across all LACA species in which the queried gene has a confidently mapped ortholog and detectable expression; the exact species set is reported with each result.

Accepts any standard HGNC gene symbol

Analysis Result

FOXO3
Spearman ฯ
+0.2059
rank correlation coefficient
P-value
0.3578
two-tailed significance
Species
22
data points
Significance
n.s.
not significant
Interpretation: The expression of FOXO3 shows a weak positive correlation with maximum lifespan (ฯ = +0.2059). However, this association is not statistically significant (P = 0.3578). Based on cross-species comparison of 22 species.

Expression vs. Maximum Lifespan

Rankโ€“Rank Plot (Spearman Basis)

Detailed Data (22 species)

# Species Common Name Expression Expr. Rank Max Lifespan (yr) Lifespan Rank
1 Amphiprion percula Orange clownfish 0.1844 11 30.0 16.5
2 Tetraodon nigroviridis Green spotted puffer 0.0322 5 10.0 8
3 Ailuropoda melanoleuca Giant panda 0.3940 16 38.0 19
4 Neovison vison American mink 0.8215 20 10.0 8
5 Gallus gallus Red junglefowl 0.8017 19 30.0 16.5
6 Taeniopygia guttata Zebra finch 0.8564 21 14.0 12
7 Anolis carolinensis Green anole 0.2768 14 7.2 5
8 Homo sapiens Human 0.9245 22 122.6 22
9 Microcebus murinus Gray mouse lemur 0.1683 9 18.2 13
10 Pan paniscus Bonobo 0.0004 1 60.0 21
11 Tupaia belangeri Northern tree shrew 0.0032 3 12.0 10.5
12 Bos taurus Cattle 0.0008 2 22.0 14
13 Equus asinus Donkey 0.1815 10 40.0 20
14 Sus scrofa Pig 0.1914 12 27.0 15
15 Cavia porcellus Guinea pig 0.4803 17 12.0 10.5
16 Heterocephalus glaber Naked mole rat 0.3727 15 37.0 18
17 Ictidomys tridecemlineatus Thirteen-lined ground squirrel 0.7696 18 10.0 8
18 Mesocricetus auratus Golden hamster 0.0121 4 4.0 2.5
19 Mus musculus House mouse 0.2158 13 4.0 2.5
20 Peromyscus maniculatus Baird's deer mouse 0.0773 7 8.0 6
21 Peromyscus polionotus Oldfield mouse 0.0763 6 5.0 4
22 Rattus norvegicus Norway rat 0.1618 8 3.8 1