Study-wide evidence portal · Cell 2023
One study, 41 mammals, six tissues
Explore the exact Table S1A inventory behind Distinct longevity mechanisms across and within species and their association with aging. This page connects each species to its deposited sample records, locally available analysis view, and exact LACA catalog match where one exists.
- Species
- 41
- Samples
- 371
- Tissues
- 6
- LACA links
- 27
Table S1A coverage
Six-tissue study universe
Counts are reconciled biological-replicate records selected from GEO SOFT or ENA metadata.
Tissue images are illustrative LACA atlas icons, not histology, study specimens, or expression results. Tissue links open representative human atlas records.
Species-to-source routing
All 41 study mammals
Filter the complete inventory without changing the underlying study scope.
Showing all 41 study mammals
| # | Species | Order | Six-tissue coverage | Study samples | Available views | LACA record |
|---|---|---|---|---|---|---|
| 01 | Spiny mouse Acomys cahirinus | Rodentia |
BR 0
CE 0
HE 0
KI 0
LI 3
TE 0
|
3 | No exact record | |
| 02 | Bowhead whale Balaena mysticetus | Cetartiodactyla |
BR 0
CE 0
HE 0
KI 4
LI 3
TE 0
|
7 | No exact record | |
| 03 | Minke whale Balaenoptera acutorostrata | Cetartiodactyla |
BR 1
CE 0
HE 1
KI 1
LI 1
TE 0
|
4 | No exact record | |
| 04 | Domestic yak Bos grunniens | Cetartiodactyla |
BR 1
CE 0
HE 1
KI 0
LI 1
TE 0
|
3 | SP391 → exact | |
| 05 | Domestic cattle Bos taurus | Cetartiodactyla |
BR 4
CE 0
HE 2
KI 4
LI 4
TE 0
|
14 | SP013 → exact | |
| 06 | Domestic dog Canis familiaris | Carnivora |
BR 2
CE 0
HE 0
KI 2
LI 2
TE 0
|
6 | SP094 → synonym | |
| 07 | Domestic goat Capra hircus | Cetartiodactyla |
BR 2
CE 0
HE 0
KI 2
LI 2
TE 0
|
6 | SP085 → synonym | |
| 08 | Canadian beaver Castor canadensis | Rodentia |
BR 2
CE 0
HE 0
KI 0
LI 2
TE 0
|
4 | No exact record | |
| 09 | Guinea pig Cavia porcellus | Rodentia |
BR 3
CE 0
HE 0
KI 3
LI 3
TE 0
|
9 | SP095 → exact | |
| 10 | Vervet Chlorocebus aethiops | Primates |
BR 1
CE 0
HE 0
KI 1
LI 1
TE 0
|
3 | SP2214 → exact | |
| 11 | Horse Equus caballus | Perissodactyla |
BR 2
CE 0
HE 0
KI 3
LI 3
TE 0
|
8 | SP102 → exact | |
| 12 | Western European hedgehog Erinaceus europaeus | Eulipotyphla |
BR 2
CE 0
HE 0
KI 2
LI 2
TE 0
|
6 | No exact record | |
| 13 | Domestic cat Felis catus | Carnivora |
BR 3
CE 0
HE 0
KI 3
LI 3
TE 0
|
9 | SP089 → exact | |
| 14 | Damaraland mole rat Fukomys damarensis | Rodentia |
BR 4
CE 0
HE 0
KI 4
LI 4
TE 2
|
14 | No exact record | |
| 15 | Gorilla Gorilla gorilla | Primates |
BR 2
CE 2
HE 2
KI 2
LI 2
TE 1
|
11 | SP200 → exact | |
| 16 | Naked mole rat Heterocephalus glaber | Rodentia |
BR 4
CE 0
HE 0
KI 4
LI 4
TE 0
|
12 | SP239 → exact | |
| 17 | Human Homo sapiens | Primates |
BR 5
CE 1
HE 2
KI 2
LI 2
TE 2
|
14 | SP121 → exact | |
| 18 | Rhesus macaque Macaca mulatta | Primates |
BR 3
CE 2
HE 2
KI 2
LI 2
TE 2
|
13 | SP020 → exact | |
| 19 | Long-tailed macaque Macaca fascicularis | Primates |
BR 0
CE 6
HE 0
KI 5
LI 6
TE 0
|
17 | SP075 → exact | |
| 20 | Asian badger Meles meles | Carnivora |
BR 2
CE 0
HE 0
KI 2
LI 2
TE 0
|
6 | No exact record | |
| 21 | Mongolian gerbil Meriones unguiculatus | Rodentia |
BR 3
CE 0
HE 0
KI 3
LI 3
TE 0
|
9 | SP493 → exact | |
| 22 | Golden hamster Mesocricetus auratus | Rodentia |
BR 3
CE 0
HE 0
KI 3
LI 3
TE 0
|
9 | SP098 → exact | |
| 23 | Short-tailed opossum Monodelphis domestica | Didelphimorphia |
BR 2
CE 2
HE 2
KI 2
LI 2
TE 2
|
12 | SP039 → exact | |
| 24 | Greater tube-nosed bat Murina leucogaster | Chiroptera |
BR 2
CE 0
HE 0
KI 1
LI 3
TE 0
|
6 | No exact record | |
| 25 | House mouse Mus musculus | Rodentia |
BR 6
CE 3
HE 3
KI 6
LI 6
TE 2
|
26 | SP124 → exact | |
| 26 | Brandt's bat Myotis brandtii | Chiroptera |
BR 3
CE 0
HE 0
KI 6
LI 6
TE 0
|
15 | No exact record | |
| 27 | Duck-billed platypus Ornithorhynchus anatinus | Monotremata |
BR 2
CE 2
HE 2
KI 2
LI 2
TE 2
|
12 | SP198 → exact | |
| 28 | Old World rabbit Oryctolagus cuniculus | Lagomorpha |
BR 2
CE 0
HE 0
KI 2
LI 2
TE 0
|
6 | SP107 → exact | |
| 29 | Bonobo Pan paniscus | Primates |
BR 3
CE 2
HE 2
KI 2
LI 2
TE 1
|
12 | SP015 → exact | |
| 30 | Chimpanzee Pan troglodytes | Primates |
BR 6
CE 2
HE 2
KI 2
LI 2
TE 1
|
15 | SP014 → exact | |
| 31 | Baboon Papio anubis | Primates |
BR 6
CE 0
HE 0
KI 6
LI 6
TE 0
|
18 | SP317 → exact | |
| 32 | White-footed mouse Peromyscus leucopus | Rodentia |
BR 3
CE 0
HE 0
KI 2
LI 3
TE 0
|
8 | No exact record | |
| 33 | Sugar glider Petaurus breviceps | Diprotodontia |
BR 2
CE 0
HE 0
KI 2
LI 2
TE 0
|
6 | SP1826 → exact | |
| 34 | Orangutan Pongo pygmaeus | Primates |
BR 2
CE 1
HE 2
KI 2
LI 2
TE 0
|
9 | No exact record | |
| 35 | Brown rat Rattus norvegicus | Rodentia |
BR 3
CE 0
HE 0
KI 3
LI 3
TE 0
|
9 | SP126 → exact | |
| 36 | House shrew Suncus murinus | Eulipotyphla |
BR 0
CE 0
HE 0
KI 0
LI 3
TE 0
|
3 | No exact record | |
| 37 | Domestic pig Sus scrofa | Cetartiodactyla |
BR 2
CE 0
HE 0
KI 2
LI 2
TE 0
|
6 | SP105 → exact | |
| 38 | Brazilian free-tailed Bat Tadarida brasiliensis | Chiroptera |
BR 0
CE 0
HE 0
KI 0
LI 3
TE 0
|
3 | No exact record | |
| 39 | Siberian chipmunk Tamias sibiricus | Rodentia |
BR 2
CE 0
HE 0
KI 2
LI 2
TE 0
|
6 | SP1847 → exact | |
| 40 | Tree shrew Tupaia belangeri | Scandentia |
BR 1
CE 0
HE 1
KI 1
LI 1
TE 1
|
5 | SP244 → exact | |
| 41 | American black bear Ursus americanus | Carnivora |
BR 2
CE 0
HE 0
KI 3
LI 2
TE 0
|
7 | No exact record |
No species match the current filters.
Published supplementary evidence
Pathways, biomarkers, and validation signals
Ranked previews are transcribed from the authors’ supplementary workbooks. Adjusted p-values, directions, and normalized enrichment scores retain the authors’ contexts.
Top pathway signals
Lowest adjusted p-value GSEA entries across supplied contexts.
-
REACTOME NEURONAL SYSTEM Brain ML · NES -2.29 · q 0.0016
-
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Brain ML · NES -2.19 · q 0.0016
-
REACTOME NEUREXINS AND NEUROLIGINS Brain ML · NES -2.17 · q 0.0016
-
GO POTASSIUM ION TRANSPORT Brain ML · NES -2.16 · q 0.0016
-
GO REGULATION OF NEUROTRANSMITTER RECEPTOR ACTIVITY Brain ML · NES -2.15 · q 0.0016
-
GO DENDRITE MORPHOGENESIS Brain ML · NES -2.15 · q 0.0016
-
REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES Brain ML · NES -2.13 · q 0.0016
-
GO VESICLE MEDIATED TRANSPORT IN SYNAPSE Brain ML · NES -2.13 · q 0.0016
-
GO REGULATION OF NERVOUS SYSTEM PROCESS Brain ML · NES -2.12 · q 0.0016
-
GO DENDRITE DEVELOPMENT Brain ML · NES -2.12 · q 0.0016
Candidate biomarkers
Lowest author-reported adjusted harmonic-mean p-value per gene.
-
Sdhb interventions · Positive · adj. HMP 2.0e-24
-
Cnp interventions · Negative · adj. HMP 1.7e-23
-
Ndufs2 interventions · Positive · adj. HMP 2.1e-19
-
Casd1 interventions · Negative · adj. HMP 1.8e-16
-
Ltn1 aging · Negative · adj. HMP 3.6e-16
-
Ndufa9 interventions · Positive · adj. HMP 7.1e-16
-
Igf1 interventions · Negative · adj. HMP 1.7e-15
-
Ndufs1 interventions · Positive · adj. HMP 1.7e-14
-
Mospd1 interventions · Positive · adj. HMP 5.4e-14
-
Rragc aging · Positive · adj. HMP 5.6e-14
Validation signals
Lowest adjusted p-value intervention or compound signals.
-
Hypoxia Liver · Interventions · NES 5.32 · q 0.00017
-
Dicer1 KO Liver · Aging · NES 6.24 · q 0.00017
-
Rap1 KO WAT · Interventions · NES -4.88 · q 0.00017
-
Rap1 KO WAT · Aging · NES 4.64 · q 0.00017
-
Rap1 KO WAT · Species · NES 2.69 · q 0.00017
-
p21 OE Skeletal muscle · Interventions · NES -5.95 · q 0.00017
-
p21 OE Skeletal muscle · Aging · NES 7.18 · q 0.00017
-
Keap1 KO Liver · Interventions · NES 2.10 · q 0.00017
Reproducibility
Manifest and source provenance
Generated 2026-08-14T10:20:04Z
SOFT/ENA accessions were matched by scientific name and reconciled deterministically to each Table S1A tissue replicate count.
PMID 37269831 · Tyshkovskiy et al.